| the first stage of syphilis, characterized by the formation of a chancre at the site of infection. |

| primary syphilis n. The first stage of syphilis, characterized by formation of a painless chancre at the point of infection and hardening and swelling of adjacent lymph nodes. |
primary syphilis n.
The first stage of syphilis, marked by formation of a painless chancre at the point of infection and by hardening and swelling of adjacent lymph nodes.