Main Entry: pro·meta·phase Pronunciation: -'met-&-"fAz Function: noun : a stage sometimes distinguished between the prophase and metaphaseof mitosis or meiosis and characterized by disappearance of the nuclear membrane and formation of the spindle
prometaphase pro·met·a·phase (prō-mět'ə-fāz') n. The stage of mitosis or meiosis in which the nuclear membrane disintegrates, the centrioles reach the poles of the cell, and the chromosomes continue to contract.