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[proh-meth-uh-zeen, -zin] /proʊˈmɛθ əˌzin, -zɪn/
noun, Pharmacology
a phenothiaxine derivative, C 1 7 H 2 0 N 2 S, used for the symptomatic relief of allergies and in the management of motion sickness.
1950-55; propyl + (di)meth(ylamine) + (phenothi)azine, components of its chemical name Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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British Dictionary definitions for promethazine


an antihistamine drug used to treat allergies and to prevent vomiting, esp in motion sickness
Word Origin
C20: from pro(pyl) + (di)meth(ylamine) + (phenothi)azine
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Encyclopedia Article for promethazine

synthetic drug used to counteract the histamine reaction, as in allergies. Promethazine, introduced into medicine in the 1940s, is used in the form of its hydrochloride. It is administered orally in tablets and syrups and intramuscularly in an aqueous solution. Promethazine is effective in controlling the symptoms of hay fever, acute skin reactions (such as hives), and contact dermatitis (as from poison ivy). It also is used to control the nausea that occurs in motion sickness. The most common side effect of promethazine is drowsiness.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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