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[proh-tuh-meen, pro-tam-in] /ˈproʊ təˌmin, prɒˈtæm ɪn/
noun, Biochemistry
any of a group of arginine-rich, strongly basic proteins that are not coagulated by heat, occurring primarily in the sperm of fish.
Origin of protamine
1870-75; prot- + amine Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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British Dictionary definitions for protamine


any of a group of basic simple proteins that occur, in association with nucleic acids, in the sperm of some fish
Word Origin
C19: from German: see proto-, amine
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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protamine in Medicine

protamine pro·ta·mine (prō'tə-mēn', -mĭn) or pro·ta·min (-mĭn)
Any of a group of simple proteins found in fish sperm that are strongly basic, are soluble in water, are not coagulated by heat, and yield chiefly arginine upon hydrolysis. In purified form, they are used in a long-acting formulation of insulin and to neutralize the anticoagulant effects of heparin.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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