noun Biochemistry.
a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue.

1969; prote(in) + -o- + glyc- + -an, variant of -ane Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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American Heritage
Medical Dictionary

proteoglycan pro·te·o·gly·can (prō'tē-ō-glī'kān', -kən)
Any of various mucopolysaccharides that are bound to protein chains in covalent complexes and occur in the extracellular matrix of connective tissue.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
The joint loses proteoglycan molecules and other tissues.
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