a normally present gene that appears to have a role in the regulation of normal cell growth, but that is converted to an oncogene by mutation. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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American Heritage
Medical Dictionary

proto-oncogene pro·to-on·co·gene (prō'tō-ŏn'kə-jēn', -ŏng'kə-)
A normal gene that has the potential to transform itself into an oncogene.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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