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1707, "offspring of a white and a mulatto," from Spanish cuarteron (used chiefly of the offspring of a European and a mestizo), literally "one who has a fourth" (Negro blood), from cuarto "fourth," from Latin quartus (see quart), so called because he or she has one quarter African blood. Altered by influence of words in quadr-. There also was some use in 19c. of quintroon (from Spanish quinteron) "one who is fifth in descent from a Negro; one who has one-sixteenth Negro blood."