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late 14c., "unbiased," from Old French indifferent "impartial" or directly from Latin indifferentem (nominative indifferens) "not differing, not particular, of not consequence, neither good nor evil," from in- "not, opposite of" (see in- (1)) + differens, present participle of differre "set apart" (see differ). Extended sense of "apathetic" first recorded early 15c.; that of "neither good nor bad" 1530s, on notion of "neither more nor less advantageous."
indifferent in·dif·fer·ent (ĭn-dĭf'ər-ənt, -dĭf'rənt)
Characterized by a lack of partiality; unbiased.
Not active or involved; neutral.
Undifferentiated, as cells or tissue.