Rat-bite fever

ratbite fever

[rat-bahyt]
noun Pathology.
either of two relapsing febrile diseases, widely distributed geographically, caused by infection with Streptobacillus moniliformis or Spirillum minor and transmitted by rats.

Origin:
1905–10; rat + bite

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World English Dictionary
ratbite fever or ratbite disease (ˈrætˌbaɪt)
 
n
pathol an acute infectious febrile disease caused by the bite of a rat infected with either of two pathogenic bacteria (Streptobacillus moniliformis or Spirillum minus)
 
ratbite disease or ratbite disease
 
n

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

rat-bite fever n.
Headache, fever, lymphangitis, and lymphadenitis following the bite of a rat or other rodent, due either to a spirillum or to Streptobacillus moniliformis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

rat-bite fever

relapsing type of infection caused by the bacterium Spirillum minus (also called Spirillum minor) and transmitted to humans by the bite of an infected rat. It is characterized by infection at the site of inoculation, inflammation of the regional lymph nodes, relapsing fever, chills, and skin rash. The rat-bite wound usually first heals promptly, but after an incubation period of 5 to 28 days there is a sudden flare-up of the characteristic symptoms, and the wound becomes swollen, hard, and painful and may ulcerate. Both local and generalized symptoms subside, only to reappear again in a few days; periods of fever may then alternate with afebrile periods. False-positive serological tests for syphilis occur in a large proportion of the cases; confirmation of the diagnosis is made by demonstration of S. minus in the lesion or regional lymph node. Treatment consists of the use of antimicrobial drugs such as penicillin and streptomycin; chlorotetracycline and oxytetracycline have also proved effective. The condition was first described in Japan (Japanese sodoku: "rat poisoning"). See also streptobacillary fever.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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