[ruh-zheem, rey-, or, sometimes, -jeem]
a mode or system of rule or government: a dictatorial regime.
a ruling or prevailing system.
a government in power.
the period during which a particular government or ruling system is in power.
Medicine/Medical, regimen ( def 1 ).
Also, régime.

1770–80; < French régime < Latin regimen regimen

regime, regimen, regiment. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
regime or régime (reɪˈʒiːm)
1.  a system of government or a particular administration: a fascist regime; the regime of Fidel Castro
2.  a social system or order
3.  med another word for regimen
[C18: from French, from Latin regimen guidance, from regere to rule]
régime or régime
[C18: from French, from Latin regimen guidance, from regere to rule]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

"system of government or rule," 1792, from Fr. régime, from L. regimen "rule, guidance, government," from regere (see regal). In Fr., l'ancien régime refers to the system of government before the revolution of 1789.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

regime re·gime (rā-zhēm', rĭ-)
A regulated system, as of diet and exercise; a regimen.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Cultural Dictionary
regime [(ray-zheem, ri-zheem)]

An administration, or a system of managing government.

The American Heritage® New Dictionary of Cultural Literacy, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Example sentences
It's no wonder that you're in support of continuing the regime of standardized
So if some people rebel, others may follow, thinking that their rebellion may
  be a sign of the regime's weakness.
Symbolically, it is the lungs of the regime, where its noxious but effective
  televised propaganda is authored.
The regime executed people who tried to adapt by engaging in private business.
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