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"piece of lace worn around the neck," 1680s, from Middle English tokker "tucker, one who dresses or finishes cloth" (see tuck).
"to tire, weary," 1833, New England slang, of uncertain origin, perhaps from tucked (past participle of tuck (v.)), which had, in reference to dogs, a slang sense of "exhausted, underfed." Related: Tuckered; tuckering.