noun, plural sanctums, sancta [sangk-tuh] .
a sacred or holy place.
an inviolably private place or retreat.

1570–80; noun use of neuter of Latin sānctus; see Sanctus Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
sanctum (ˈsæŋktəm)
n , pl -tums, -ta
1.  a sacred or holy place
2.  a room or place of total privacy or inviolability
[C16: from Latin, from sanctus holy]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

1577, from L. sanctum "a holy place," as in L.L. sanctum sanctorum "holy of holies" (from Gk. to hagion ton hagion, from Heb. qodesh haqqodashim), from neut. of sanctus "holy" (see saint). In Eng., sanctum sanctorum attested from c.1400; sense of "a person's private retreat" is from 1706.
Online Etymology Dictionary, © 2010 Douglas Harper
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