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scleroderma

/ˌsklɪərəʊˈdɜːmə/
noun
1.
a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin
Word Origin
C19: from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
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