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inoculation in·oc·u·la·tion (ĭ-nŏk'yə-lā'shən)
The act or an instance of inoculating, especially the introduction of an antigenic substance or vaccine into the body to produce immunity to a specific disease.
process of producing immunity and method of vaccination that consists of introduction of the infectious agent onto an abraded or absorptive skin surface instead of inserting the substance in the tissues by means of a hollow needle, as in injection. Of the common vaccines, only smallpox vaccine is routinely inoculated. The term inoculation is also commonly used more broadly to mean any introduction of antigenic substances into the tissues. See also immunization; vaccine.