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"harem," also the name of a former palace of the sultan in Istanbul, 1580s, from Italian seraglio, alteration of Turkish saray "palace, court," from Persian sara'i "palace, inn," from Iranian base *thraya- "to protect" (cf. Avestan thrayeinti "they protect"), from PIE *tra-, variant form of root *tere- "to cross over, pass through, overcome" (see through).
The Italian word probably reflects folk etymology influence of serraglio "enclosure, cage," from Medieval Latin serraculum "bung, stopper" (see serried).
in Istanbul, collection of classical antiquities, manuscripts, ceramics, armour, textiles, and other artifacts, housed in the sultans' Seraglio (Topkapi Saray). It was established in 1892 and later extended