| 1. | Biochemistry. the principal protein of blood plasma, important in osmotic regulation of the blood and transport of metabolites. |
| 2. | the commercial form of this substance, used in dye preparations, foodstuffs, and in medicine esp. in the treatment of shock. |
| serum albumin n. A protein fraction of serum involved in maintaining osmotic pressure of the blood and used as a substitute for plasma in the treatment of shock. |
serum albumin n.
See seralbumin.
serum albumin
protein found in blood plasma that helps maintain the osmotic pressure between the blood vessels and tissues. Serum albumin accounts for 55 percent of the total protein in blood plasma. Circulating blood tends to force fluid out of the blood vessels and into the tissues, where it results in edema (swelling from excess fluid). The colloid nature of albumin-and, to a lesser extent, of other blood proteins called globulins-keeps the fluid within the blood vessels. Albumin also acts as a carrier for two materials necessary for the control of blood clotting: (1) antithrombin, which keeps the clotting enzyme thrombin from working unless needed, and (2) heparin cofactor, which is necessary for the anticlotting action of heparin. The serum albumin level falls and rises in such liver disorders as cirrhosis or hepatitis. Transfusions of serum albumin are used to combat shock and whenever it is necessary to remove excess fluid from the tissues. Similar albumin compounds with other functions occur in plants, animal tissues, egg whites, and milk.
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