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serum sickness

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serum sickness

–noun Pathology.
a generalized allergic reaction to a foreign serum or drug, characterized by fever, skin rash, enlarged lymph nodes, and painful joints.
Also called serum disease.


Origin:
1910–15
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2009.
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serum sickness  
n.  A hypersensitive reaction to the administration of a foreign serum, characterized by fever, swelling, skin rash, and enlargement of the lymph nodes.
The American Heritage® Dictionary of the English Language, Fourth Edition
Copyright © 2009 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Medical Dictionary

Main Entry: serum sickness
Function: noun
: an allergic reaction to the injection of foreign serum manifested by hives, swelling, eruption, arthritis, and fever calledalso serum disease
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

serum sickness n.
A hypersensitive reaction to the administration of a foreign serum, marked by fever, swelling, skin rash, and lymph node enlargement. Also called serum disease, serum reaction.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia

serum sickness

an allergic reaction to animal serum or antiserum injected into an individual's blood to provide immunity against such illnesses as tetanus, botulism, and snake-venom poisoning. Symptoms include skin eruption, itching, swelling of the face and extremities, fever, joint pain and sometimes swelling, abdominal pain, nausea, and vomiting; severe cases may also show neurological symptoms.

Learn more about serum sickness with a free trial on Britannica.com.

Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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