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A hypodermic injection.
A small amount given or applied at one time.
Something that boosts one's spirits: “After my recent financial troubles, that raise was a real shot in the arm.”
beaver shot, call the shots, cheap shot, drop case, give something a shot, give something one's best shot, grab shot, half-shot, have a crack at something, hot shot, long shot, mug shot, not by a long shot, one-shot
[the drinking senses are shortenings of an early 1800s expression shot in the neck, meaning both ''a drink'' and ''drunk''; shoot, ''to guess,'' is found by 1864]