Medical Dictionary
Main Entry:
Shwartz·man reaction Pronunciation:
'shworts-m&n-, 'shwärts- Function:
noun : either of two reactions resulting fromadministration of endotoxin to experimental animals and especially rabbits:
a : a generalized reaction following two intravenous injections of endotoxin given 24 hours apart and markedby widespread hemorrhage, reduced numbers of white blood cells and platelets, renal necrosis, and death of the animal called also
generalized Shwartzman reaction b : a localizedcutaneous reaction following subcutaneous injection of endotoxin followed 24 hours later by intravenous injection of endotoxin and marked by hemorrhage, necrosis, and white blood cell infiltration atthe site of first injection called also
Shwartzman phenomenon
