side effect

any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.
any accompanying or consequential and usually detrimental effect: the side effects of air pollution.
Also, side-effect.

1880–85 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
side effect
1.  Compare aftereffect any unwanted nontherapeutic effect caused by a drug
2.  any secondary effect, esp an undesirable one

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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American Heritage
Medical Dictionary

side effect n.
A peripheral or secondary effect, especially an undesirable secondary effect of a drug or therapeutic regimen.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
Furthermore, the satellite measurements have helped flag a worrying side effect
  of excessive groundwater extraction.
Germ theory, which secularized infectious disease, had a side effect: it
  sacralized epidemiology.
In fact, such image correction is merely a side effect of what is genuinely
  different about the technology.
The side effect is that whatever is on the oven floor cooks extremely quickly.
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