side effect

any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.
any accompanying or consequential and usually detrimental effect: the side effects of air pollution.
Also, side-effect.

1880–85 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
side effect
1.  Compare aftereffect any unwanted nontherapeutic effect caused by a drug
2.  any secondary effect, esp an undesirable one

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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American Heritage
Medical Dictionary

side effect n.
A peripheral or secondary effect, especially an undesirable secondary effect of a drug or therapeutic regimen.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
But nearly all failed because of the difficulties of getting a working gene
  into cells without also causing harmful side effects.
There were some side effects to the development of our skull position.
Half of those who participated in the poll expressed concern about possible
  side effects.
The side effects of unrestrained credit growth turned out to be devastating.
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