(in prescriptions) write; mark; label: indicating directions to be written on a package or label for the use of the patient. Origin: < L signā;See signa
A distinctive mark, characteristic, or sound indicating identity: A surprise ending is the signature of an O. Henry short story.
Abbr. Sig. or S.Medicine The part of a physician's prescription containing directions to the patient.
Music
A sign used to indicate key.
A sign used to indicate tempo.
A letter, number, or symbol placed at the bottom of the first page on each sheet of printed pages of a book as a guide to the proper sequence of the sheets in binding.
A large sheet printed with four or a multiple of four pages that when folded becomes a section of the book.
Printing
A letter, number, or symbol placed at the bottom of the first page on each sheet of printed pages of a book as a guide to the proper sequence of the sheets in binding.
A large sheet printed with four or a multiple of four pages that when folded becomes a section of the book.
[French, from Old French, from Medieval Latin signātūra, from Latin signātus, past participle of signāre, to mark, from signum, sign; see sign.]
si·gnor also si·gnior (sēn-yôr', -yōr') n.
pl.si·gno·ri (sēn-yôr'ē, -yō'rē) also si·gniors or si·gnors Abbr. Sig. or S. Used as a courtesy title for a man in an Italian-speaking area, equivalent to Mr.
[Italian, variant of signore; see signore.]
si·gno·re (sēn-yôr'ā, -yōr'ā, -yō'rě) n.
pl.si·gno·ri (-yôr'ē, -yō'rē) Abbr. Sig. or S. Used as a form of polite address for a man in an Italian-speaking area.
(sĭg'nə-chər) 
