a token; indication.
any object, action, event, pattern, etc., that conveys a meaning.
a conventional or arbitrary mark, figure, or symbol used as an abbreviation for the word or words it represents.
a motion or gesture used to express or convey an idea, command, decision, etc.: Her nod was a sign that it was time to leave.
a notice, bearing a name, direction, warning, or advertisement, that is displayed or posted for public view: a traffic sign; a store sign.
a trace; vestige: There wasn't a sign of them.
an arbitrary or conventional symbol used in musical notation to indicate tonality, tempo, etc.
Medicine/Medical. the objective indications of a disease.
any meaningful gestural unit belonging to a sign language.
an omen; portent: a sign of approaching decadence.
sign language ( def 1 ).
Usually, signs. traces, as footprints, of a wild animal.
a plus sign or minus sign used as a symbol for indicating addition or subtraction.
a plus sign or minus sign used as a symbol for indicating the positive or negative value of a quantity, as an integer.
a symbol, as or !, used to indicate a radical or factorial operation.
verb (used with object)
to affix a signature to: to sign a letter.
to write as a signature: to sign one's name.
to engage by written agreement: to sign a new player.
to mark with a sign, especially the sign of the cross.
to communicate by means of a sign; signal: He signed his wish to leave.
to convey (a message) in a sign language.
Obsolete. to direct or appoint by a sign.
verb (used without object)
to write one's signature, as a token of agreement, obligation, receipt, etc.: to sign for a package.
to make a sign or signal: He signed to her to go away.
to employ a sign language for communication.
to obligate oneself by signature: He signed with another team for the next season.
Verb phrases
sign away/over, to assign or dispose of by affixing one's signature to a document: She signed over her fortune to the church.
sign in, to record or authorize one's arrival (or departure) by signing a register. Also, sign out.
sign off,
to withdraw, as from some responsibility or connection.
to cease radio or television broadcasting, especially at the end of the day.
Informal. to become silent: He had exhausted conversation topics and signed off.
to indicate one's approval explicitly if not formally: The president is expected to sign off on the new agreement.
sign on,
to employ; hire.
to bind oneself to work, as by signing a contract: He signed on as a pitcher with a major-league team.
to start radio or television broadcasting, especially at the beginning of the day.
Computers. log1 ( def 17a ).
sign up, to enlist, as in an organization or group; to register or subscribe: to sign up for the navy; to sign up for class.

1175–1225; (noun) Middle English signe < Old French < Latin signum mark, sign, ensign, signal, image; (v.) Middle English signen to mark with a sign, especially the sign of the cross < Old French signer < Latin signāre to mark with a sign, inscribe, affix a seal to, derivative of signum

signless, adjective
signlike, adjective
postsign, verb (used with object)
unsigned, adjective

sign, sing (see synonym study at the current entry).

1. trace, hint, suggestion. 1, 4. signal. 10. indication, hint, augury. Sign, omen, portent name that which gives evidence of a future event. Sign is a general word for whatever gives evidence of an event—past, present, or future: Dark clouds are a sign of rain or snow. An omen is an augury or warning of things to come; it is used only of the future, in general, as good or bad: birds of evil omen. Portent limited, like omen to prophecy of the future, may be used of a specific event, usually a misfortune: portents of war. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
sign (saɪn)
1.  something that indicates or acts as a token of a fact, condition, etc, that is not immediately or outwardly observable
2.  an action or gesture intended to convey information, a command, etc
3.  a.  a board, placard, etc, displayed in public and inscribed with words or designs intended to inform, warn, etc
 b.  (as modifier): a sign painter
4.  an arbitrary or conventional mark or device that stands for a word, phrase, etc
5.  maths, logic
 a.  any symbol indicating an operation: a plus sign; an implication sign
 b.  the positivity or negativity of a number, quantity, or expression: subtraction from zero changes the sign of an expression
6.  an indication or vestige: the house showed no signs of being occupied
7.  a portentous or significant event
8.  an indication, such as a scent or spoor, of the presence of an animal
9.  med Compare symptom any objective evidence of the presence of a disease or disorder
10.  astrology Compare sign of the zodiac
vb (often foll by to)
11.  to write (one's name) as a signature to (a document, etc) in attestation, confirmation, ratification, etc
12.  to make a sign; signal
13.  to engage or be engaged by written agreement, as a player for a team, etc
14.  (tr) to outline in gestures a sign over, esp the sign of the cross
15.  (tr) to indicate by or as if by a sign; betoken
16.  (intr) to use sign language
[C13: from Old French signe, from Latin signum a sign]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

early 13c., "gesture or motion of the hand," from O.Fr. signe "sign, mark, signature," from L. signum "mark, token, indication, symbol," from PIE base *sekw- "point out" (see see). Meaning "a mark or device having some special importance" is recorded from late 13c.; that of
"a miracle" is from c.1300. Sense of "characteristic device attached to the front of an inn, shop, etc., to distinguish it from others" is first recorded mid-15c. Ousted native token. In some uses, the word probably is aphetic for ensign. First record of signage is from 1976. Sign language is recorded from 1847.

c.1300, "to make the sign of the cross," from O.Fr. signer, from L. signare, from signum (see sign (n.)). Sense of "to mark, stamp" is attested from mid-14c.; that of "to affix one's name" is from late 15c. Meaning "to communicate by sign language" is recorded from 1700.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

sign (sīn)

  1. See symptom.

  2. Something that suggests the presence or existence of a fact, condition, or quality.

  3. A trace or vestige, as of disease or life.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
sign   (sīn)  Pronunciation Key 
  1. A body manifestation, usually detected on physical examination or through laboratory tests or xrays, that indicates the presence of abnormality or disease. Compare symptom.

  2. See symbol. See Table at symbol.

The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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