importance; consequence: the significance of the new treaty.
meaning; import: The familiar place had a new significance for her.
the quality of being significant or having a meaning: to give significance to dull chores.

1400–50; late Middle English (< Middle French) < Latin significantia force, meaning, equivalent to significant- (see significant) + -ia -ia; see -ance

nonsignificance, noun
self-significance, noun

1. moment, weight. See importance. 2. See meaning.

1. triviality. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
significance (sɪɡˈnɪfɪkəns)
1.  consequence or importance
2.  something signified, expressed, or intended
3.  the state or quality of being significant
4.  statistics
 a.  a measure of the confidence that can be placed in a result, esp a substantive causal hypothesis, as not being merely a matter of chance
 b.  Compare confidence level See also hypothesis testing (as modifier): a significance level

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

c.1300, from L. significantia "meaning, force, energy," from significans, prp. of significare (see signify).
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Given the importance the administration had attached to this matter, this would
  have seemed news of the utmost significance.
Giving chocolate as a gift takes on new significance when it comes from your
  own kitchen.
In the coming months, commentators around the world would look back at this
  moment and debate its significance.
The past or the significance of the episode isn't relevant.
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