| 1. | the outer layer of the skin of a snake, which is cast off periodically. |
| 2. | Pathology. a mass or layer of dead tissue separated from the surrounding or underlying tissue. |
| 3. | anything that is shed or cast off. |
| 4. | Cards. a discard. |
| 5. | to be or become shed or cast off, as the slough of a snake. |
| 6. | to cast off a slough. |
| 7. | Pathology. to separate from the sound flesh, as a slough. |
| 8. | Cards. to discard a card or cards. |
| 9. | to dispose or get rid of; cast (often fol. by off): to slough off a bad habit. |
| 10. | to shed as or like a slough. |
| 11. | Cards. to discard (cards). |
| 12. | slough over, to treat as slight or trivial: to slough over a friend's mistake. |

slough (slŭf)
n.
A layer or mass of dead tissue separated from surrounding living tissue, as in a wound, a sore, or an inflammation. v. sloughed, slough·ing, sloughs
To separate from surrounding living tissue. Used of dead tissue.
| slough (slŭf) Pronunciation Key
Noun The dead outer skin shed by a reptile or an amphibian. Verb To shed an outer layer of skin. |