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[splee-nuh-meg-uh-lee, splen-uh-] /ˌspli nəˈmɛg ə li, ˌsplɛn ə-/
noun, Pathology
enlargement of the spleen.
Also, splenomegalia
[splee-noh-muh-gey-lee-uh, -geyl-yuh, splen-oh-] /ˌspli noʊ məˈgeɪ li ə, -ˈgeɪl yə, ˌsplɛn oʊ-/ (Show IPA)
1895-1900; spleno- + -megaly Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the web for splenomegaly
  • Approach to the patient with lymphadenopathy and splenomegaly.
British Dictionary definitions for splenomegaly


(pathol) abnormal enlargement of the spleen
Word Origin
C20: from Greek splēno-, from splēnspleen + megalo-, from megas large + -y³
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for splenomegaly

enlargement of the spleen, 1900, from spleno-, comb. form of Greek splen (see spleen) + megas "great" (fem. megale; see mickle).

Online Etymology Dictionary, © 2010 Douglas Harper
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splenomegaly in Medicine

splenomegaly sple·no·meg·a·ly (splē'nō-měg'ə-lē, splěn'ō-)
Enlargement of the spleen. Also called megalosplenia.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Article for splenomegaly

enlargement of the spleen, the abdominal organ that serves as a temporary storage site for blood and filters out degenerated and old blood cells. Splenomegaly may arise as a symptom of a number of diseases, including certain systemic infections, inflammatory diseases, hematologic diseases, inherited spleen disorders, cysts, and neoplastic diseases. In one form of the disorder, called congestive splenomegaly, the spleen becomes engorged with blood because of impaired flow through the splenic vein, which empties into the portal vein. Such impairment may be caused by liver disease, portal vein or splenic vein pathology, constrictive pericarditis, or congestive cardiac failure.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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