splenomegaly

[splee-nuh-meg-uh-lee, splen-uh-]
noun Pathology.
enlargement of the spleen.
Also, splenomegalia [splee-noh-muh-gey-lee-uh, -geyl-yuh, splen-oh-] .


Origin:
1895–1900; spleno- + -megaly

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Collins
World English Dictionary
splenomegaly (ˌspliːnəʊˈmɛɡəlɪ)
 
n
pathol abnormal enlargement of the spleen
 
[C20: from Greek splēno-, from splēnspleen + megalo-, from megas large + -y³]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

splenomegaly sple·no·meg·a·ly (splē'nō-měg'ə-lē, splěn'ō-)
n.
Enlargement of the spleen. Also called megalosplenia.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

splenomegaly

enlargement of the spleen, the abdominal organ that serves as a temporary storage site for blood and filters out degenerated and old blood cells. Splenomegaly may arise as a symptom of a number of diseases, including certain systemic infections, inflammatory diseases, hematologic diseases, inherited spleen disorders, cysts, and neoplastic diseases. In one form of the disorder, called congestive splenomegaly, the spleen becomes engorged with blood because of impaired flow through the splenic vein, which empties into the portal vein. Such impairment may be caused by liver disease, portal vein or splenic vein pathology, constrictive pericarditis, or congestive cardiac failure.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
Approach to the patient with lymphadenopathy and splenomegaly.
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