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"courageous," 1811, originally of fist fights. To stand (someone) up "fail to keep an appointment" is attested from 1902. Stand-up comic first attested 1966.
Courageous and personally accountable; bold; gutsy • Most often in the expression stand-up guy: He handled the humiliating defeat like a stand-up guy/ And he's very, very stand-up (1841+)noun
A live interview at the scene of a news event: I hang a left past the faded Rose law firm and the networks doing evening stand-ups at the entrance (1990s+ Televison)
[adjective sense perhaps fr stand up and be counted]