statin

statin

[stat-n]
noun Pharmacology.
any of a class of drugs that reduce the levels of lipids in the blood by altering the enzyme activity in the liver that produces lipids: used in the prevention and treatment of heart disease.
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World English Dictionary
statin (ˈstætɪn)
 
n
any of a class of drugs, including atorvastatin and simvastatin, that lower the levels of low-density lipoproteins in the blood by inhibiting the activity of an enzyme involved in the production of cholesterol in the liver

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

statin stat·in (stāt'n)
n.
Any of a class of drugs that reduce serum cholesterol levels by inhibiting a key enzyme involved in the biosynthesis of cholesterol.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
statin   (stāt'n)  Pronunciation Key 
Any of a class of drugs that inhibit a key enzyme involved in the synthesis of cholesterol and promote receptor binding of LDL-cholesterol, resulting in decreased levels of serum cholesterol and LDL-cholesterol and increased levels of HDL-cholesterol.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Encyclopedia Britannica
Encyclopedia

statin

drug that acts to lower cholesterol levels by inhibiting the enzyme HMG-CoA (5-hydroxy-3-methylglutaryl-coenzyme A) reductase, which is required for cholesterol synthesis. Examples of statins include simvastatin, pravastatin, and lovastatin. Statins are generally quite safe, but side effects may include muscle pain and fatigue. A rare side effect called myopathy, characterized by muscle degeneration, has been associated with a mutation in a gene involved in mediating liver uptake of statins.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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