1. To feel pain or distress; sustain loss, injury, harm, or punishment.
2. To tolerate or endure evil, injury, pain, or death. See Synonyms at bear¹.
3. To appear at a disadvantage: "He suffers by comparison with his greater contemporary" (Albert C. Baugh).

1. To undergo or sustain (something painful, injurious, or unpleasant): "Ordinary men have always had to suffer the history their leaders were making" (Herbert J. Muller).
2. To experience; undergo: suffer a change in staff.
3. To endure or bear; stand: would not suffer fools.
4. To permit; allow: "They were not suffered to aspire to so exalted a position as that of streetcar conductor" (Edmund S. Morgan).

Usage Note: In general usage the preferred preposition after suffer is from, rather than with, in constructions such as He suffered from hypertension. Ninety-four percent of the Usage Panel found suffered with unacceptable in the preceding example. In medical usage suffer with is sometimes employed with reference to the pain or discomfort caused by a condition, while suffer from is used more broadly in reference to a condition, such as anemia, that is detrimental but not necessarily painful.