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Tay-Sachs disease

[tey-saks] /ˈteɪˈsæks/
noun, Pathology
1.
a rare fatal hereditary disease, occurring chiefly in infants and children, especially of eastern European Jewish origin, characterized by a red spot on the retina, gradual blindness, and paralysis.
Origin
1920-1925
1920-25; named after W. Tay (1843-1927), English physician, and B. Sachs (1858-1944), American neurologist
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for tay-sachs dis-ease

Tay-Sachs disease

/ˌteɪˈsæks/
noun
1.
an inherited disorder, caused by a faulty recessive gene, in which lipids accumulate in the brain, leading to mental retardation and blindness. It occurs mostly in Ashkenazi Jews
Word Origin
C20: named after W. Tay (1843–1927), British physician, and B. Sachs (1858–1944), US neurologist
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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tay-sachs dis-ease in Medicine

Tay-Sachs disease (tā'sāks')
n.
A lyposomal storage disease that is the infantile type of cerebral sphingolipidosis. Also called GM2 gangliosidosis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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tay-sachs dis-ease in Science
Tay-Sachs disease
  (tā'sāks')   
A genetic disease in which the products of fat metabolism accumulate in the nervous system, causing retardation, paralysis, and death by preschool age. Individuals of eastern European Jewish descent have a higher risk of inheriting Tay-Sachs disease. The disease is named after its describers, British ophthalmologist Warren Tay (1843-1927) and American neurologist Bernard Sachs (1858-1944).
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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