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Tay-Sachs disease (tā'sāks')
A lyposomal storage disease that is the infantile type of cerebral sphingolipidosis. Also called GM2 gangliosidosis.
|Tay-Sachs disease |
A genetic disease in which the products of fat metabolism accumulate in the nervous system, causing retardation, paralysis, and death by preschool age. Individuals of eastern European Jewish descent have a higher risk of inheriting Tay-Sachs disease. The disease is named after its describers, British ophthalmologist Warren Tay (1843-1927) and American neurologist Bernard Sachs (1858-1944).