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telomere

[tel-uh-meer, tee-luh‐] /ˈtɛl əˌmɪər, ˈti lə‐/
noun
1.
the segment of DNA that occurs at the ends of chromosomes.
Origin
1935-1940
1935-40
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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Examples from the web for telomeres
  • The limit is presumed to occur because the structures at the end of chromosomes, called telomeres, reach a critical length.
  • The first drug targeting telomeres, now sold as a nutritional supplement, will soon face the harsh light of peer review.
  • telomeres are known to have important roles in the development of cancers and in the aging process.
British Dictionary definitions for telomeres

telomere

/ˈtɛləˌmɪə/
noun
1.
(genetics) either of the ends of a chromosome
Word Origin
C20: from Greek telos end + meros part
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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telomeres in Medicine

telomere tel·o·mere (těl'ə-mēr', tē'lə-)
n.
Either end of a chromosome; a terminal chromosome.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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telomeres in Science
telomere
  (těl'ə-mîr', tē'lə-)   
Either of the sections of DNA occurring at the extreme ends of each chromosome in a eukaryotic cell. Telomeres consist of highly repetitive sequences of DNA that do not code for proteins, but function as caps to keep chromosomes from fusing together. The length of the telomere influences the stability of genetic information just interior of the telomere, since the nucleotide sequences at the ends of a chromosome are not copied by DNA polymerase. Successive copying can thus shorten telomeres, sometimes to the point that functional genes near the telomeres are lost, and this may play a role in cellular senescence and age-related diseases. In germ cells, stem cells, and some cancer cells, shortened telomeres can be extended by the enzyme telomerase, thus keeping both the telomeres and the genes near them functioning. Most somatic cells do not express telomerase, and the shortening of telomeres during each round of cell division may be part of the natural aging of cells.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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telomeres in Culture
telomere [(tel-uh-meer)]

The long end sequences of a DNA strand occuring at the tip of the chromosomes; a type of repetitive DNA that usually consists of one hundred to fifteen hundred copies of a single DNA sequence.

Note: During DNA replication, small parts of the telomere are lost with each cycle. Scientists think that this loss may be related to the aging process.
The American Heritage® New Dictionary of Cultural Literacy, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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