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thrombocytopathy throm·bo·cy·top·a·thy (thrŏm'bō-sī-tŏp'ə-thē)
A disorder of the blood coagulating mechanism that results from dysfunction of the platelets.
any of several blood disorders characterized by dysfunctional platelets (thrombocytes), which result in prolonged bleeding time, defective clot formation, and a tendency to hemorrhage. Inherited thrombocytopathies include von Willebrand disease; thrombasthenia, characterized by abnormal clot retraction and defective platelet aggregation; and Bernard-Soulier syndrome, characterized by unusually large platelets. In addition, thrombocytopathy is sometimes seen in cases of Down syndrome and Wiskott-Aldrich syndrome (an immune disorder).