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type I familial hyperlipoproteinemia n.
Familial hyperlipoproteinemia marked by the increased serum concentrations of chylomicrons and triglycerides, which decrease if the diet becomes fat-free, decreased concentrations of high- and low-density lipoproteins, which increase if the diet is fat-free diet, and decreased tissue lipoprotein lipase activity. It is marked by paroxysms of abdominal pain, enlargement of the spleen and liver, and eruptive xanthomas. Also called familial fat-induced hyperlipemia, familial hyperchylomicronemia, familial hypertriglyceridemia.