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city, seat (1784) of Fayette county, southwestern Pennsylvania, U.S. It lies along Redstone Creek, among the rugged foothills of the Allegheny Mountains, 45 miles (72 km) southeast of Pittsburgh. Settled in 1768 and laid out (1776) by Henry Beeson, a Quaker, it was first known as Beeson's Town. Its location on the old Cumberland (National) Road was an important factor in its early development