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upstream

[uhp-streem] /ˈʌpˈstrim/
adverb
1.
toward or in the higher part of a stream; against the current.
adjective
2.
directed upstream; situated upstream:
an upstream journey; an upstream hideout.
3.
Commerce. of or pertaining to the early stages in the operations of a business or industry, as exploration and production in the oil business (opposed to downstream).
4.
against or opposite to the direction of transcription, translation, or synthesis of a DNA, RNA, or protein molecule.
Origin
1675-1685
1675-85; up- + stream
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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British Dictionary definitions for up-stream

upstream

/ˈʌpˈstriːm/
adverb, adjective
1.
in or towards the higher part of a stream; against the current
2.
(in the oil industry) of or for any of the stages prior to oil production, such as exploration or research Compare downstream (sense 2)
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for up-stream
upstream
1681, from up- + stream. In common use from c.1890.
Online Etymology Dictionary, © 2010 Douglas Harper
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