noun Biology.
a membrane-bound cavity within a cell, often containing a watery liquid or secretion. See diag. under cell.
a minute cavity or vesicle in organic tissue.

1850–55; < French; see vacuum, -ole1

vacuolar [vak-yoo-oh-ler, vak-yoo-uh-, vak-yuh-ler] , adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
vacuole (ˈvækjʊˌəʊl)
biology a fluid-filled cavity in the cytoplasm of a cell
[C19: from French, literally: little vacuum, from Latin vacuum]

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Medical Dictionary

vacuole vac·u·ole (vāk'yōō-ōl')

  1. A small cavity in the cytoplasm of a cell, bound by a single membrane and containing water, food, or metabolic waste.

  2. A small space or cavity in a tissue.

vac'u·o'lar (-ō'lər, -lär') adj.
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Science Dictionary
vacuole   (vāk'y-ōl')  Pronunciation Key 
A cavity within the cytoplasm of a cell, surrounded by a single membrane and containing fluid, food, or metabolic waste. Vacuoles are found in the cells of plants, protists, and some primitive animals. In mature plant cells, there is usually one large vacuole which occupies a large part of the cell's volume and is filled with a liquid called cell sap. The cell sap stores food reserves, pigments, defensive toxins, and waste products to be expelled or broken down. In the cells of protists, however, there may be many small specialized vacuoles, such as digestive vacuoles for the absorption of captured food and contractile vacuoles for the expulsion of excess water or wastes. See more at cell.
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