a small sac or cyst.
Biology. a small bladderlike cavity, especially one filled with fluid.
Pathology. a circumscribed elevation of the epidermis containing serous fluid; blister.
Geology. a small, usually spherical cavity in a rock or mineral, formed by expansion of a gas or vapor before the enclosing body solidified.

1570–80; < Latin vēsīcula little bladder. See vesica, -ule Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
vesicle (ˈvɛsɪkəl)
1.  pathol
 a.  any small sac or cavity, esp one containing serous fluid
 b.  a blister
2.  geology a rounded cavity within a rock formed during solidification by expansion of the gases present in the magma
3.  botany a small bladder-like cavity occurring in certain seaweeds and aquatic plants
4.  any small cavity or cell
[C16: from Latin vēsīcula, diminutive of vesica]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

1578, from M.Fr. vesicule, from L. vesicula, dim. of vesica "bladder, blister."
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

vesicle ves·i·cle (věs'ĭ-kəl)

  1. A small structure resembling a bladder.

  2. A small circumscribed elevation of the skin containing serum.

  3. A small sac or cyst containing liquid or gas.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
vesicle   (věs'ĭ-kəl)  Pronunciation Key 
  1. A small fluid-filled sac in the body.

  2. A membrane-bound sac in eukaryotic cells that stores or transports the products of metabolism in the cell and is sometimes the site for the breaking down of metabolic wastes. Vesicles bulge out and break off from the endoplasmic reticulum and the Golgi apparatus. Vesicles get their energy for mobility from ATP. Lysosomes and peroxisomes are vesicles.

  3. A small cavity formed in volcanic rock by entrapment of a gas bubble during solidification.

vesicular adjective (vě-sĭk'yə-lər, və-)
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
The primary divisions of the brain are visible, and the optic and auditory
  vesicles are formed.
It was a wonderful surprise--the whole slide began to fill with these beautiful
  little vesicles.
The gene manufactures a protein that binds monoamines into packages, called
  vesicles, for transportation between neurons.
Once forged, the vesicles grew by incorporating additional fatty acids.
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