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waterhouse-friderichsen syndrome

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Medical Dictionary

Main Entry: Wa·ter·house–Frid·er·ich·sen syndrome
Pronunciation: 'wot-&r-"haus-'frid-(&-)rik-s&n-
Function: noun
: acute and severe meningococcemia with hemorrhage into the adrenal glands
Waterhouse, Rupert (1873–1958), British physician, and Friderichsen,Carl (b 1886), Danish physician. Waterhouse described in 1911 a syndrome of acute collapse associated with hemorrhages in the adrenal glands, usually observed in severecases of meningitis caused by the meningococcus. Friderichsen published his own independent description of the syndrome in 1918.
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

Waterhouse-Friderichsen syndrome Wa·ter·house-Frid·er·ich·sen syndrome (wô'tər-hous'frĭd'ə-rĭk'sən)
n.
Acute fulminating meningococcal septicemia occurring mainly in children under 10 years old and characterized by vomiting, diarrhea, extensive purpura, cyanosis, convulsions, and circulatory collapse, usually accompanied by meningitis and hemorrhage into the adrenal glands.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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