In the customary or expected order, naturally, as in The new minister did not, of course, fire the church secretary. This usage, first recorded in 1548, employs course in the sense of "ordinary procedure."
Certainly, as in Of course I'll answer the phone, or Are you going to the meeting?Of course. [Early 1800s] Also see matter of course.
Dictionary.com presents 366 FAQs, incorporating some of the frequently asked questions from the past with newer queries.