Separate and reserve for a special purpose, as in We have to set aside some chairs for latecomers. [Early 1700s] Also see set by.
Discard or reject, as in Setting aside all health considerations, do you believe this law is fair to smokers? [Early 1400s]
Declare invalid, annul, or overrule, as in The higher court set aside the conviction. [Mid-1700s] Also see lay aside.