Medical Dictionary

tolerance tol·er·ance (tŏl'ər-əns)

  1. Decreased responsiveness to a stimulus, especially over a period of continued exposure.

  2. The capacity to absorb a drug continuously or in large doses without adverse effect; diminution in the response to a drug after prolonged use.

  3. Physiological resistance to a poison.

  4. Acceptance of a tissue graft or transplant without immunological rejection.

  5. Unresponsiveness to an antigen that normally produces an immunological reaction.

  6. The ability of an organism to resist or survive infection by a parasitic or pathogenic organism.

tol'er·ant adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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