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fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged Cooley's anaemia , Cooley's anemia , thalassaemia major , thalassemia major
state of being homozygous; having two identical alleles of the same gene homozygosity
hybrid produced by crossing parents that are homozygous except for a single gene locus that has two alleles (as in Mendel's experiments with garden peas) monohybrid
cross between an organism whose genotype for a certain trait is unknown and an organism that is homozygous recessive for that trait so the unknown genotype can be determined from that of the offspring test-cross , testcross
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