cinchonine

[ sing-kuh-neen, -nin, sin- ]

Phonetic (Standard)IPA

noun

, Pharmacology.

a colorless, crystalline, slightly water-soluble alkaloid, C 19 H 22 N 2 O, a stereoisomer of cinchonidine, obtained from the bark of various species of cinchona and used chiefly as a quinine substitute.

cinchonine

/ ˈsɪŋkəˌniːn /

an insoluble crystalline alkaloid isolated from cinchona bark, used to treat malaria. Formula: C 19 H 22 N 2 O

First recorded in 1815–25; cinchon(a) + -ine ²

The operation is then repeated, the ether being replaced by chloroform in which both quinine and cinchonine are soluble.

Red bark contains not only quinine and cinchonine, but also cinchonidine.

Cinchonine may be prepared from its sulphate or disulphate in the same way as quinine.

It is stated that incomplete examinations have detected cinchonine in the bark.

When cinchonine is distilled with solid potassium hydrate, it yields pyrrol and bases of both the pyridine and quinoline series.

April 23, 2024inveterate

[in-vet-er-it ]

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