In 1620 most people considered the likelihood of reversing the seasons inside a building impossible, and many deemed it sacrilege, an attempt to contravene the natural order, to twist the configuration of the world established by God.
-- Tom Shachtman, Absolute Zero and the Conquest of Cold
Anorexics, for example, clearly contravene our evolutionary dictate to eat.
-- Jerry A. Coyne, "Of Vice and Men", The New Republic, April 3, 2000