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a combining form used in the formation of compound words that have the general sense “lack, deficiency,” as specified by the initial element:
Origin of -penia
< New Latin, combining form representing Greek penía poverty, need Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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-penia in Medicine

-penia suff.
Lack; deficiency: leukopenia.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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