verb (used without object)
to go away; leave: She departed from Paris today. The train departs at 10:52.
to diverge or deviate (usually followed by from ): The new method departs from the old in several respects.
to pass away, as from life or existence; die.
verb (used with object)
to go away from; leave: to depart this life.
Archaic. departure; death.

1175–1225; Middle English departen < Old French departir, equivalent to de- de- + partir to go away; see part (v.)

undeparting, adjective

1. Depart, retire, retreat, withdraw imply leaving a place. Depart is a somewhat literary word for going away from a place: to depart on a journey. Retire emphasizes absenting oneself or drawing back from a place: to retire from a position in battle. Retreat implies a necessary withdrawal, especially as a result of adverse fortune in war: to retreat to secondary lines of defense. Withdraw suggests leaving some specific place or situation, usually for some definite and often unpleasant reason: to withdraw from a hopeless task. 4. quit.

1. arrive. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
depart (dɪˈpɑːt)
1.  to go away; leave
2.  to start out; set forth
3.  (usually foll by from) to deviate; differ; vary: to depart from normal procedure
4.  (tr) to quit (archaic, except in the phrase depart this life)
[C13: from Old French departir, from de- + partir to go away, divide, from Latin partīrī to divide, distribute, from pars a part]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

early 13c., from O.Fr. departir, from L.L. departire "divide" (transitive), from de- "from" + partire "to part, divide," from pars (gen. partis) "a part." As a euphemism for "to die" (to depart this life) it is attested from c.1500. Transitive in Eng. lingers in some senses;
the wedding service was till death us depart until 1662.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Boats leave heavily laden, and many depart even without a satellite phone to use when trouble arises.
Editors at some houses have limited authority to depart from house style.
But researchers wanted to know why sons sometimes stay home over the winter and
  sometimes depart.
So along come the punctuated equilibrium postulates which deepen the mire
  because you completely depart from long term evolvement.
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