Know why cattywampus was trending last week?
lupus lu·pus (lōō'pəs)
Any of several diseases, especially systemic lupus erythematosus, that principally affect the skin and joints but often also involve other systems of the body.
See systemic lupus erythematosus.
An autoimmune disease that tends to strike women more frequently than men. The disease attacks the body's connective tissues.