[mis-iz, miz-iz]
plural Mmes. [mey-dahm, -dam]
a title of respect prefixed to the name of a married woman: Mrs. Jones.
a title prefixed to a mock surname that is used to represent possession of a particular attribute, identity, etc., especially in an idealized or excessive way: Mrs. Punctuality.

abbreviation of mistress

Mrs, Ms.

See Ms.

Mrs., first recorded in the early 17th century, was originally, like Miss, an abbreviation of mistress. Mrs. and mistress were at first used interchangeably in all contexts, but by the second half of that century, the written form of the abbreviation was largely confined to use as a title preceding a woman's surname. By the early 19th century, reduction of the medial consonant cluster had contracted the usual pronunciation of the title from [mis-tris] to [mis-is] or [mis-iz]. The contracted pronunciation used other than as a title was not considered standard, and today, locutions like Let me discuss it with the missis are perceived as old-fashioned. Currently, two main types of pronunciation for the abbreviation occur in the United States; [mis-iz] and sometimes [mis-is] are the common forms in the North and North Midland, while in the South Midland and South, the prevalent types are [miz-iz] and [miz] the latter homophonous with the usual pronunciation of the abbreviation Ms. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
Mrs (ˈmɪsɪz)
n , pl Mrs, Mesdames
a title used before the name or names of a married woman
[C17: originally an abbreviation of mistress]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1582, abbreviation of mistress (q.v.), originally in all uses of that word. The pl. Mmes. is an abbreviation of Fr. mesdames, pl. of madame. Pronunciation "missis" was considered vulgar at least into 18c. The Mrs. "one's wife" is from 1920.
Online Etymology Dictionary, © 2010 Douglas Harper
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Computing Dictionary

MRS definition

Modifiable Representation System.
An integration of logic programming into Lisp.
["A Modifiable Representation System", M. Genesereth et al, HPP 80-22, CS Dept Stanford U 1980].

The Free On-line Dictionary of Computing, © Denis Howe 2010
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American Heritage
Abbreviations & Acronyms
Used as a courtesy title for a married or widowed woman (from "mistress")
  1. media recognition system

  2. medical review systems

The American Heritage® Abbreviations Dictionary, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Example sentences for Mrs
Tingle fell short of election in wit, and in that teaching mrs.
In one of the episodes she appeared to have the same dress as mrs.
Stepping into her own room after a brief word with dorothy, mrs.
Her position was undercut when it was revealed in one episode that, while mrs.
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